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In summary, mitochondria-lysosome interactions play a critical role in regulating ROS and metabolic signaling, highlighting their importance not only in material turnover but also as key hubs for cellular stress sensing and the maintenance of functional homeostasis (Fig

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Gadoteridol was found to be eliminated more rapidly from rat cerebellum, cerebrum, and skin, compared to gadoteric acid and to gadobutrol, in the first 5 weeks after repeated administration of these macrocyclic GBCAs, resulting in lower levels of retained Gd (III) in these tissues [130]